Adolescent Exposure to WIN 55212-2 Render the Nigrostriatal Dopaminergic Pathway Activated During Adulthood
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چکیده
منابع مشابه
Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice
Chronic cannabinoid consumption is an increasingly common behavior among teenagers and has been shown to cause long-lasting neurobehavioral alterations. Besides, it has been demonstrated that cocaine addiction in adulthood is highly correlated with cannabis abuse during adolescence. Cocaine consumption and subsequent abstinence from it can cause psychiatric symptoms, such as psychosis, cognitiv...
متن کاملDestructive Effects of Prenatal WIN 55212-2 Exposure on Central Nervous System of Neonatal Rats
Background: Cannabinoid, particularly hashish and WIN 55212-2 (WIN), consumption during embryonic period may affect fetal growth, and the development of motor functioning, memory and cognitive functions. Therefore, the present study aimed to evaluate the effects of WIN 55212-2 during embryonic period on behavioral responses, as well as tissue and memory changes among neonatal rats. Methods: WIN...
متن کاملDestructive Effects of Prenatal WIN 55212-2 Exposure on Central Nervous System of Neonatal Rats
BACKGROUND Cannabinoid, particularly hashish and WIN 55212-2 (WIN), consumption during embryonic period may affect fetal growth, and the development of motor functioning, memory and cognitive functions. Therefore, the present study aimed to evaluate the effects of WIN 55212-2 during embryonic period on behavioral responses, as well as tissue and memory changes among neonatal rats. METHODS WIN...
متن کاملCorrigendum to “Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait”
[This corrects the article DOI: 10.1155/2016/6481862.].
متن کاملRepeated heat exposure impairs nigrostriatal dopaminergic neurons in mice.
Environmental heat stress is associated with physical stress responses, including changes in monoamines, protein expression, and neuronal circuits and damage to neurons in the brain. This study determined the effects of heat stress on the nigrostriatal dopaminergic system based on behavioral, histological, and neurochemical analyses. To evaluate behavioral changes after heat exposure, we subjec...
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ژورنال
عنوان ژورنال: International Journal of Neuropsychopharmacology
سال: 2020
ISSN: 1461-1457,1469-5111
DOI: 10.1093/ijnp/pyaa053